Refractory Multiple Myeloma market (2025-2030)
The Refractory Multiple Myeloma market focuses on the treatment of multiple myeloma (MM) cases that do not respond to standard therapies or relapse after initial treatment. Multiple myeloma is a cancer of the plasma cells, and the refractory form signifies resistance to conventional therapies such as chemotherapy and immunomodulatory agents. This market includes novel therapies targeting various aspects of the disease pathophysiology, including immune modulation, proteasome inhibition, and monoclonal antibody therapies.
Disruptive Impact and Opportunities:
The refractory multiple myeloma market is witnessing a paradigm shift driven by the development of novel, targeted therapies that offer hope for patients who have exhausted conventional treatment options. These treatments have the potential to redefine care by providing more effective solutions for patients with relapsed or refractory disease, offering improved survival outcomes, and reducing side effects. New immunotherapy approaches, including bispecific antibodies and CAR-T cell therapies, present a major opportunity for healthcare providers to offer safer, more targeted treatments with fewer adverse effects. As patients and clinicians demand more personalized, efficient, and cost-effective therapies, the market is set to experience a surge in innovation, creating a wealth of opportunities for companies that can deliver these advancements.
Emerging Drugs:
- NEXI 002
- AMG-701
- ABBV 453
Marketed Drugs:
- Bortezomib
- Carfilzomib (Kyprolis)
- Ixazomib (Ninlaro)
Key Companies:
- NexImmune
- Amgen
- AbbVie
- Allogene Therapeutics
- Precision Biosciences
- Takeda Oncology
- ORIC Pharmaceuticals
- Ionis Pharmaceuticals
- Cellectis S.A.
- YZY Biopharma
- Janssen Research & Development
- Bristol Myers Squibb
- Lava Therapeutics
- Prelude Therapeutics
Market Segmentation:
By Type of Treatment:
- Proteasome Inhibitors
- Bortezomib (Velcade)
- Carfilzomib (Kyprolis)
- Ixazomib (Ninlaro)
- Immunomodulatory Drugs (IMiDs)
- Lenalidomide (Revlimid)
- Pomalidomide (Pomalyst)
- Monoclonal Antibodies
- Daratumumab (Darzalex)
- Elotuzumab (Empliciti)
- Isatuximab (Sarclisa)
- Immunotherapies and Cell-based Therapies
- CAR-T Cell Therapy
- Abecma (ide-cel)
- Carvykti (ciltacabtagene autoleucel)
- Bispecific T-cell Engagers
- AMG 701
- BCMA/CD3-targeted therapies
- Other Targeted Therapies
- Venetoclax (Venclexta)
- Selinexor (Xpovio)
- Melflufen (Pepaxto)
By Administration Type:
- Oral Administration
- Lenalidomide (Revlimid)
- Pomalidomide (Pomalyst)
- Ixazomib (Ninlaro)
- Venetoclax (Venclexta)
- Selinexor (Xpovio)
- Intravenous Administration
- Bortezomib (Velcade)
- Carfilzomib (Kyprolis)
- Daratumumab (Darzalex)
- Isatuximab (Sarclisa)
- Abecma (ide-cel)
- Carvykti (ciltacabtagene autoleucel)
What’s in It for You?
- Uncover the latest trends and advancements in refractory multiple myeloma treatment
- Identify key emerging therapies poised to disrupt the market
- Gain insights into leading companies and their market strategies
- Assess the growth potential of the refractory multiple myeloma segment and key therapeutic areas
- Understand how new innovations could redefine patient care and treatment paradigms
- Refractory Multiple Myeloma Market- Executive Summary
- Introduction
- Objectives
- Key Findings
- Market Size 2025 & 2030: By Key Country (10MM)
- Global Market Size 2025 & 2030: By Key Segment
- Key Investments & Startup Analysis
- Research Methodology
- Understanding the Disease
- Disease Overview
- Classification
- Signs and Symptoms
- Risk Factors
- Causes
- Disease Biology & Digital Innovations
- Stages & Staging System
- Diagnostic Algorithm
- Current Treatment Practices & Algorithm
- Current Standard of Care and Treatment Gaps
- Patient Demographics and Treatment Pathways
- Guidelines
- Unmet Needs
- Epidemiology and Patient Population
- Epidemiology Key Findings
- Assumptions and Rationale: 10MM
- Epidemiology Scenario: 10MM
- U.S. Epidemiology Scenario
- EU-5 Epidemiology
- U.K. Epidemiology Scenario
- Germany Epidemiology Scenario
- France Epidemiology Scenario
- Italy Epidemiology Scenario
- Spain Epidemiology Scenario
- Japan Epidemiology Scenario
- China Epidemiology Scenario
- Australia Epidemiology Scenario
- India Epidemiology Scenario
- Real-world Data & Real-world Evidence
- Drug Development Landscape
- Existing Key Drug Candidate Profiles/ Marketed Therapies
- Competitive Analysis and Differentiation
- Overview of Similar/Competing Drugs in Clinical Trials
- Future Trends and Emerging Drugs
- Regulatory Strategy and Potential Challenges
- Regulatory Pathways in Key Markets
- Anticipated Regulatory Hurdles and Mitigation Strategies
- Case Studies in Oncology Drug Regulation
- Impact of Potential Changes to Regulatory Framework
- Commercial Landscape
- Market Size & Growth Rates
- Key Approvals & Anticipated Loss of Exclusivity
- PESTLE & Porter’s Five Forces Analysis
- Market Shares, Positioning/Ranking
- Market Drivers
- Identification of Threats
- Digital Evolution in Commercialization
- Market Segmentation
- Pricing, Reimbursement, and Access
- Competitive Pricing Analysis
- Reimbursement Landscape and Challenges
- Strategies for Market Access and Equity
- Patient Spending/Expenditure Analysis
- Future Trends, Disruptions, and Opportunities
- Analysis of Emerging Trends
- Technological Impact
- Impact of Potential Market Disruptors
- Opportunities for Future Development and Expansion
- Considerations for Investment Opportunities
- Global Market Dynamics
- Regional Regulatory Disparities
- Cross-Border Partnership Strategies
- Global Supply Chain Dynamics
- Case Studies: Success and Failure in Global Markets
- Strategies for Global Expansion and Localization
- Company Profiles