Protein A Resins Market Size Analysis (2023 - 2030)

The global Protein A Resins Market size was worth USD 0.9 billion in 2022 and is expected to reach USD 1.9 billion with a CAGR of 11.9% during the forecast period 2023 - 2030. 

Protein A resins are used to prepare a large number of pure materials to identify traces of contaminants in the product. 99% of the purity can be obtained in generic form. 

The novel corona virus (COVID-19) has driven pharmaceutical and biopharmaceutical companies, drug developers, and research institutes to get back on other diagnostic segments. The COVID-19 has shifted its focus to research on chronic disease treatment. Protein A resin is used to purify the antibodies, and the rise in monoclonal antibodies production because of the present COVID-19 upsurges the market growth. During the pandemic period, stimulating consumption is due to growing mAb production. 

Market Drivers

The global Protein A resins market is driven by factors like rising demand for therapies for antibodies and the growing number of research and development activities. The need for monoclonal antibodies is surging for treating chronic diseases boosts the demand for Protein A resin market growth. In 2022, an estimation of 1,762,450 new cancer cases was recorded and 606,880cancer death cases were registered in the U.S. as per the American Cancer Society. Governments across the globe are spending high capital on research and development activities which escalates the Protein A resin market growth. Factors like pre-packed disposable columns and rising demand for therapeutic antibodies poise the Protein A resins market growth during the forecast period.

Factors like stimulating diagnostic and therapeutic applications of monoclonal antibodies for controlling chronic diseases, and rising demand for detecting and preventing the diseases at the early stages. 

Market Restrains

The cost of the Protein A resin market is expensive which hinders the market growth. The costs range from USD 15,000 to USD 16,000 per liter.

PROTEIN A RESINS MARKET REPORT COVERAGE

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Segmentation Analysis

The global Protein A Resins Market is segmented and sub-segmented based on the product, type, application, and end-user.

Protein A Resins Market - By Product

• Agarose-based Protein A
• Glass/Silica-based Protein A
• Organic Polymer-based Protein A

By product, the Agarose-based protein A segment is dominating the protein A resin market. The segment growth depends on factors like the wide use of matrix resin for the attachment of ligands that combine proteins. 

The segment Glass/Silica is expected to witness significant growth due to developing durability, the potentiality to combine high metal dopant absorption, and mechanical strength.

Protein A Resins Market - By Type

• Recombinant Protein A
• Natural Protein A

By type, the recombinant protein A segment reigns the market with the highest share. The segment growth depends on increasing repeated use of recombinant protein A resins throughout the production of monoclonal antibodies. 

Protein A Resins Market - By Application

• Antibody Purification
• Immunoprecipitation

Antibody purification application segment commands for highest share in the Protein A resin market in 2022. Growing demand for monoclonal antibodies used for therapies along with research studies, and 
also used in downstream processing of antibodies. 

The immunoprecipitation application segment projected the largest growth due to wide applicability in the R&D area. 

Protein A Resins Market - By End-User

• Pharmaceutical & Biopharmaceutical Companies
• Academic Research Institutes
• Clinical Research Laboratories
• Other End Users

By end-user, pharmaceutical, and biopharmaceutical companies govern the Protein A resins market across the historical period. One major factor that drives the end-user segment is surging research and development expenses. 

Regional Analysis

Geographically, North America is leading the Protein A resin market with the largest share throughout the historical period. The growth in the region owes to augmenting the need for pharmaceuticals and biopharmaceuticals. U.S is dominating the Protein A resins market throughout the region. Around USD 79.6 billion was spent on research and development activities by the biopharmaceutical and pharmaceutical companies in the U.S, in 2018. 48 drugs were approved as new biologics or molecular entities in 2022, as per the Centre for Drug Evaluation and Research. The market growth in the U.S. is due to the growing occurrence of chronic diseases, and the rising number of protein-related research activities. 

The European Protein A resins market is expected to have an outstanding growth rate during the timeline period. Europe is the second region globally in the protein A resin market. Nearly 66 medicines and 30 novel active substances were accepted in Europe, as per the European Medicine Agency, in 2022. In 2017, the European Federation of Pharmaceutical Companies spent 38,404 USD million on research and development activities. The market in the region depends on factors like growing knowledge about the advantages and market expansion by launching new products and devices by market players. 

Throughout the timeline period, the Asia-Pacific region is expected to have the quickest development in the Protein A resin market. The growth in the region owes to advancements in technology, rising utilization of biomaterial in drug research, and enhancing demand for vaccines and other therapies. The increasing use of Protein A resin for drug discovery fuels the market growth in APAC. Japan is accounted to hold the largest share in the region due to mounting expenses on research and development activities in developing new and advanced drugs. The growing older population generates the superior need for the availability of economical drugs, providing new opportunities for the market players in Japan. 

However, the Latin American Protein A resin market is projected to grow with the quickest CAGR growth rate. Factors like increasing demand for approximately determining new ligands, enhancing quick purification kits, and rising R&D trends of novel treatments. 

The Middle East & African Protein A resins market is anticipated to have a notable growth during the historical period. The public and private organizations are investing high capital to harden the market growth over the developed regions of MEA. 

Key Market Players in Protein A Resins Market

GE Healthcare (US), GenScript Biotech Corporation (China), Repligen Corporation (US), Thermo Fisher Scientific (US), Tosoh Bioscience (Japan), Purolite Corporation (US), Merck Millipore (Germany), Agilent Technologies (US), PerkinElmer (US), Bio-Rad Laboratories (US), Orochem (US), Kaneka Corporation (Japan), Novasep Holding SAS (France), Abcam (UK), Agarose Bead Technologies (US), Avantor (US), JSR Life Sciences (US), (Sweden), Bio-Works Technologies, Amikozen Co. Ltd. (US), and Takara Bio Inc. (Japan) are some major players operating in the Protein A Resins market. 

In January 2022, General Electric Company made a contract with Danaher Corporation. The contract is for the sale of its biopharma business.

In May 2022, the researchers from the Massachusetts Institute of Technology developed a protocol for quickly producing protein chains up to 164 amino acids.

Notable Happenings in the global Protein A Resins Market

• On 25 September 2017, GE Healthcare launched a new protein A resin. The launch is to develop monoclonal antibody purification capacity among its biopharma customers.