The global market size of nucleic acid extraction and purification systems was worth USD 3.6 billion in 2022. The market is expected to grow with a CAGR of 9.2% to reach a growth of USD 5.2 billion by 2030 throughout the foreseen period.
Nucleic acid extraction and purification is a common process in forensic analysis and molecular biology. Nucleic acid is the starting point for ample downstream applications and the quality of nucleic acids in the sample plays a vital role in defining the success of the ensuing steps of analysis.
The nucleic acid samples are generated by this technique are then used for diversified purposes like cloning, sequencing, polymerase chain reaction (PCR), and others.
Moreover, nucleic acid isolation and purification are done to increase or manipulate or purify the nucleic acid to understand the complicated details of the biological systems. Nucleic acid extraction is the key step for any amplification experiment and is an important step in the development and performance of any successful molecular diagnostic method.
The growing research and development activities and initiatives in molecular biology and precision medicine, and the demand for biologics are surging, and the growth in investments in genomics research drive the nucleic acid extraction and purification systems market. Also, next-generation sequencing (NGS) techniques and liquid biopsies are quickly adopted for detecting cancer.
However, the shortage of expert technicians and the less acceptance pace of the techniques hinder the market. The cost of the equipment is too expensive to hamper the market growth
Based on the product, the kits and reagents segment accounted for the largest share in terms of revenue. The market growth attributes to the growing utilization of kits and reagents during RNA and DNA isolation processes with growing demand for research studies. Also, the convenience of kits and reagents is developing fueling the segment growth during the foreseeable period.
Based on the type, the RNA isolation, and purification segment holds the largest share in the market. The market is expected to have a considerable CAGR growth in terms of revenue due to the blooming need for RNA isolation for COVID-19 diagnostics and the increasing deployment of mRNA for constructing cDNA libraries.
The Column-based Isolation and Purification method holds the highest market share. The method is more simple, quicker, and economical compared to organic extraction. The segment can be automated too.
By application, the diagnostics segment is said to lead the nucleic acid extraction and purification systems market with the highest share.
By end-user, the pharmaceutical and biotechnology companies are awaited to experience brisk growth owing to growing research and developmental activities for drug development.
However, the hospitals and diagnostic centers segment is scheduled to extend significantly during the timeline period. The demand for initial stage screening and disease diagnosis and infections in an economical, exact, and time-efficient manner.
North America dominated the nucleic acid extraction and purification market. The region accounts for the largest share in terms of revenue with 37.0% in 2022. The use of downstream processes is high that propels the market growth. Quick technological advancements with an array of applications of nucleic acid testing over diagnostics boost the market growth. Also, the regional growth depends on the increase in the funds for research and developments in the healthcare and biotechnology fields.
The U.S is the major contributor in the region. In the U.S., Hemophilia A affects 5,000 male births as per the CDC. Around 400 babies are born with Hemophilia A every year. The appearance of well-established healthcare infrastructure flourishes the regional market growth.
The European market for nucleic acid isolation and purification systems is outlined to have strong growth owing to the economic strength to acquire costly tools, and approving reimbursement policies.
However, Asia-Pacific is the quickest-growing region in the nucleic acid isolation and purification systems market. Public and private companies are increasingly committing towards genomics research and a quick rise in adopting isolation procedures. China is projected to hold the largest share in the market due to the quick rise in DNA or RNA libraries for Next-Generation Sequencing (NGS).
Latin American market is contemplated to grow with stable and continuous growth with a share of 12.4% in nucleic acid isolation and purification systems. Brazil is the largest country in LATAM followed by Mexico and Argentina. The increasing investments and funds for research and developments from the government, wide range of applications nucleic acid tests, and technological advancements. The above-mentioned factors boost the market growth.
The Middle East and African market is anticipated to have sluggish growth in the nucleic acid isolation and purification systems market. Private organizations play a vital role in capitalizing on the healthcare domain. In Africa, 50% and more investments are being undertaken.
Major key players in the global market
1. QIAGEN N.V. (Netherlands)
2. Thermo Fisher Scientific (US)
3. F. Hoffmann-La Roche Ltd. (Switzerland)
4. Promega Corporation (US)
5. Agilent Technologies (US)
6. Bio-Rad Laboratories (US)
7. Danaher Corporation (US),
8. GEHealthcare (US)
9. Illumina, Inc. (US)
10. Merck KGaA (Germany)
11. Takara Bio (Japan)
12. Zymo Research (US)
13. New England Biolabs (US)
14. NorgenBiotek Corp (Canada)
15. Omega Bio-tek (US)
16. Genaxxon Bioscience GmbH(Germany)
17. 3B BlackBio Biotech India Limited (India)
18. Invitek Molecular (Germany)
19. BioVision (US)
20. Analytik Jena AG (Germany)
COVID-19 Impact On Nucleic Acid Extraction and Purification Systems Market
The recent coronavirus (COVID-19) has positively impacted the nucleic acid isolation and purification systems market owing to the growth in the production of assays and kits for discovering the appearance of the COVID-19. The market players and suppliers are involved in advancing systematic, structured, and quick isolation and detection kits to avoid the virus spread.
The pharmaceutical and biotechnology industries are launching new diagnostic solutions for identifying advancing infections and diseases. For example, in June 2022, Omega-Biotek, Inc. introduced the Mag-Bind Viral RNA Xpress Kit for the effectiveness and isolation of viral RNA. The company also announced to have a production capacity of 6million tests per month. The launch of the new product has brought striking growth across the production capabilities.
Recent Market Developments
Chapter 1. Global Nucleic Acid Extraction and Purification Systems Market – Scope & Methodology
1.1. Market Segmentation
1.3. Research Methodology
1.4. Primary Sources
1.5. Secondary Sources
Chapter 2. Global Nucleic Acid Extraction and Purification Systems Market – Executive Summary
2.1. Market Size & Forecast – (2021 – 2027) ($M/$Bn)
2.2. Key Trends & Insights
2.3. COVID-19 Impact Analysis
2.3.1. Impact during 2022 - 2027
2.3.2. Impact on Supply – Demand
Chapter 3. Global Nucleic Acid Extraction and Purification Systems Market – Competition Scenario
3.1. Market Share Analysis
3.2. Product Benchmarking
3.3. Competitive Strategy & Development Scenario
3.4. Competitive Pricing Analysis
3.5. Supplier - Distributor Analysis
Chapter 4. Global Nucleic Acid Extraction and Purification Systems Market Entry Scenario
4.1. Case Studies – Start-up/Thriving Companies
4.2. Regulatory Scenario - By Region
4.3 Customer Analysis
4.4. Porter's Five Force Model
4.4.1. Bargaining Power of Suppliers
4.4.2. Bargaining Powers of Customers
4.4.3. Threat of New Entrants
4.4.4. Rivalry among Existing Players
4.4.5. Threat of Substitutes
Chapter 5. Global Nucleic Acid Extraction and Purification Systems Market - Landscape
5.1. Value Chain Analysis – Key Stakeholders Impact Analysis
5.2. Market Drivers
5.3. Market Restraints/Challenges
5.4. Market Opportunities
Chapter 6. Global Nucleic Acid Extraction and Purification Systems Market – By Product
Chapter 7. Global Nucleic Acid Extraction and Purification Systems Market – By Type
7.1. DNA Isolation & Purification
7.2. Genomic DNA Isolation & Purification
7.2. Plasmid DNA Isolation & Purification
7.2. Viral DNA Isolation & Purification
7.3. RNA Isolation & Purification
7.3.1. miRNA Isolation & Purification
7.3.2. mRNA Isolation & Purification
7.3.3. Total RNA Isolation & Purification
Chapter 8. Global Nucleic Acid Extraction and Purification Systems Market – By Method
8.1. Column-based Isolation and Purification
8.2. Magnetic Bead-based Isolation and Purification
8.3. Reagent-based Isolation and Purification
8.4. Other Isolation and Purification Methods
Chapter 9. Global Nucleic Acid Extraction and Purification Systems Market – By Application
9.2. Drug Discovery & Development
9.3. Personalized Medicine
9.4. Agriculture & Animal Research
9.5. Other Applications
Chapter 10. Global Nucleic Acid Extraction and Purification Systems Market – By End-User
10.1. Academic Research Institutes
10.2. Pharmaceutical & Biotechnology Companies
10.3. Contract Research Organizations
10.4. Hospitals and Diagnostic Centers
10.5. Other End-use
Chapter 11. Global Nucleic Acid Extraction and Purification Systems Market, By Geography - Market Size, Forecast, Trends & Insights
10.1. North America
11.2.7. Rest of Europe
11.3. Asia Pacific
11.3.2. South Korea
11.3.5. Australia & New Zealand
11.3.6. Rest of Asia-Pacific
11.4. Rest of the World
11.4.1. Middle East
11.4.3. South America
Chapter 12. Global Nucleic Acid Extraction and Purification Systems Market – Company Profiles – (Overview, Product Portfolio, Financials, Developments)
12.1. Company 1
12.2. Company 2
12.3. Company 3
12.4. Company 4
12.5 Company 5
12.6. Company 6
12.7. Company 7
12.8. Company 8
12.9. Company 9
12.10. Company 10
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