Intratumoral Cancer Therapies Market (2025-2030)

The Intratumoral Cancer Therapies Market encompasses a rapidly evolving segment focused on direct tumor-targeted treatment modalities that enhance localized efficacy while minimizing systemic toxicity. These therapies, including oncolytic viruses, gene therapies, immune modulators, and nanoparticle-based drug delivery systems, are transforming the oncology landscape by enabling precise tumor control, immune system activation, and improved patient outcomes.

Disruptive Impact & Opportunities:

Innovations in intratumoral cancer therapies are revolutionizing oncology by introducing novel approaches that enhance treatment precision and patient tolerability. The integration of oncolytic viruses and immune-stimulatory agents presents a paradigm shift, making cancer treatment more effective and accessible. Minimally invasive delivery techniques and biocompatible drug formulations are increasing adoption rates, ensuring a safer alternative to conventional systemic therapies. The market potential is expanding, driven by rising demand for personalized oncology solutions and the growing body of clinical evidence supporting intratumoral therapies.

Emerging Drugs:

• Vidutolimod (CMP-001)
• Tavokinogene telseplasmid (Tavo)
• RP1 (Vusolimogene Oderparepvec)
• INT230-6 (Cisplatin/vinblastine)
• NanoPac (LSAM Paclitaxel)
• LOAd703 (delolimogene mupadenorepvec)
• Intuvax (Ilixadencel)

Marketed Drugs:

• Delytact (teserpaturev/G47∆/ DS-1647)
• Imlygic (Talimogene laherparepvec; T-VEC)
• Hensify (NBTXR3/ PEP503)

Key Companies:

• Daiichi Sankyo
• Amgen
• Idera Pharmaceuticals
• Philogen
• Oncolys BioPharma
• Highlight Therapeutics
• Momotaro-Gene
• Ziopharm
• Takara Bio
• NanOlogy
• SillaJen
• Hookipa Biotech GmbH
• Lokon Pharma AB
• Checkmate Pharmaceuticals
• Istari Oncology
• Vyriad
• Merck Sharp & Dohme Corp.
• OncoSec Medical Incorporated
• AiViva Biopharma
• Immunicum AB
• Exicure
• Immunovative Therapies
• Provectus Biopharmaceuticals
• Sirnaomics
• Apexigen
• Replimune
• Merck & Co (Viralytics)
• Moderna Therapeutics
• Intensity Therapeutics
• DNAtrix
• Treovir
   

Market Segmentation:

By Type

• Immunotherapies
  • Oncolytic Viruses
  • Cytokine-Based Therapies
  • Cancer Vaccines
  • Immune Checkpoint Modulators
• Chemotherapeutic Agents
  • Intratumoral Chemotherapy
  • Alkylating Agents
  • Antimetabolites
• Gene Therapies
  • Viral Vector-Based Gene Therapies
  • Non-Viral Vector-Based Gene Therapies
• Targeted Therapies
  • Small Molecule Inhibitors
  • Monoclonal Antibodies
• Radionuclide Therapies
  • Injectable Radiopharmaceuticals
  • Brachytherapy-Based Intratumoral Radiotherapy
• Combination Therapies
  • Multimodal Approaches (Immunotherapy + Chemotherapy, Radiotherapy + Immunotherapy)
• Others

By Administration Type

• Intratumoral Injection
  • Direct Tumor Injection
  • Image-Guided Injection (Ultrasound, CT, MRI)
• Catheter-Based Administration
  • Intra-Arterial Infusion
  • Intra-Tumoral Microcatheters
• Implantable Drug Delivery Systems
  • Biodegradable Implants
  • Drug-Eluting Beads
• Electroporation-Assisted Drug Delivery
• Others

What’s in It for You?

• Understand the key drivers, challenges, and future outlook of intratumoral cancer therapies.
• Gain insights into emerging therapies, clinical developments, and competitor strategies.
• Identify high-potential assets and strategic alliances for business expansion.
• Navigate evolving regulatory frameworks and optimize commercialization strategies.
• Assess how cutting-edge technologies are reshaping oncology treatment paradigms.