Nitric Oxide Supplements Market Research Report – Segmentation By Type (L- Arginine and L- Citrulline); Application (Health and Fitness, and Cosmetics & Personal Care); Region – Size, Share, Growth Analysis | Forecast (2023 – 2030)

Global Nitric Oxide Supplements Market Size (2023 – 2030)

According to our research report, the global Nitric Oxide Supplement market was valued at $890.56 million in 2022, and is projected to reach a market size of $1530.15 million by 2030. The market is projected to grow with a CAGR of 7% per annum during the period of analysis (2023 - 2030).


Industry Overview

Over the past two decades, physiology and pharmacology research has undergone a revolution led by nitric oxide (NO). This labile molecule is crucial for several bodily processes, including platelet activity, vasodilation, blood flow, and mitochondrial respiration. There are now two physiological mechanisms known to be used for NO synthesis: those that depend on NO synthase (NOS) and those that don't. L-arginine is the primary precursor in the first case. It is well known that the NOS enzymes cause this amino acid to be oxidised to NO.

A particular class of amino acid known as arginine is found naturally in the human body as well as in trace amounts in various foods, including peanuts, almonds, walnuts, and pecans. The need for arginine supplementation is brought on by the body's need for it and its absence of it in nature. L-arginine is a dietary supplement that is beneficial for several ailments, including migraine and inflammation. L-arginine aids in blood vessel relaxation, which is advantageous for those with cardiovascular issues. The market is being driven by the L-expanded arginines and varied applications in daily life.

The use of supplements containing L-arginine is advised to meet the requirement for conditional amino acids. It is advised that people with protein shortage or malnutrition concerns take supplements containing L-arginine. To maintain their growth, however, youngsters who are growing need a sufficient amount of L-arginine in their diets.

Impact of Covid-19 on the Industry

Due to the effects of COVID-19, the conversion of arginine from the core components into practical products for use has been halted. Due to this, the product's inventory has decreased, and the industry's revenue has also decreased. L-arginine manufacturing has been hampered by supply chain interruption, which has also decreased store inventory. As a result, there is an imbalance between the supply of the product and market demand.

Market Drivers

Rising demand for L-arginine in the fitness industry will drive the market growth

Since arginine supplements are vital for bodybuilders who frequent the gym, the fitness sector has a significant impact on market demand. In addition to this, arginine is used in the creation of a variety of healthy foods, beverages, and sports nutrition for athletes and fitness lovers. This increases market demand because shifting customer tastes are raising awareness of health and fitness.

The surge in the usage of L-arginine in cosmetics and personal care

The market for L-arginine is booming, which suggests that the product has a wide range of applications and several uses. The rising use of L-arginine in personal care and cosmetics products spurs market expansion by giving the top market participants chances for diversification and growth.

L-arginine aids in moisturizing and maintaining the moisture of the skin. It boosts collagen synthesis and shields the skin from free radical damage. Major cell constituents such as collagen, the cell membrane, and DNA are all negatively impacted by free radicals. The antioxidant capabilities of L-arginine work to prevent the fine lines and wrinkles that these free radicals also generate. Consumer interest in applying L-arginine increases due to its expanding benefits in personal care products.

Market Restraints

The use of L-arginine might cause side effects that will challenge the market growth

In addition to indigestion, nausea, headaches, bloating, diarrhea, gout, blood irregularities, allergies, airway inflammation, exacerbation of asthma symptoms, impaired insulin sensitivity, and low blood pressure, L-arginine can also result in several other negative effects.  Higher doses of L-arginine may make heartburn, ulcers, or digestive trouble brought on by medication worse since it might raise stomach acid. L-arginine may also make herpes patients' symptoms worse.




Market Size Available

2023 - 2030

Base Year


Forecast Period

2023 - 2030



Segments Covered

By Type, Application and Region

Various Analyses Covered

Global, Regional & Country Level Analysis, Segment-Level Analysis, DROC, PESTLE Analysis, Porter’s Five Forces Analysis, Competitive Landscape, Analyst Overview on Investment Opportunities

Regional Scope

North America, Europe, APAC, Latin America, Middle East & Africa

Key Companies Profiled

Jarrow Formulas Inc., Prinova Group LLC., Glanbia Nutritionals Inc., NOW Foods, Twinlab Corporation, Infinite Labs, Olympian Labs Inc., Ajinomoto Group, Scientific Sports Nutrition Ltd.

This research report on the global nitric oxide supplements market has been segmented and sub-segmented based on, and Geography & region.

Global Nitric Oxide Supplements Market- By Type

  • L- Arginine
  • L- citrulline

Based on Type, the global nitric oxide supplement market is segmented into L-arginine and L-citrulline. The L-arginine segment is estimated to grow with the highest CAGR as it is highly demanded in the health and fitness industry as a performance enhancement supplement. Demand for L-arginine is anticipated to increase over the forecast period due to growing applications in the pharmaceutical industry. It might be created in a lab and used as a medication. L-arginine is primarily used to treat conditions related to the heart and blood vessels, such as high blood pressure, coronary artery disease, peripheral vascular disease, and chest pain (angina), as well as recovery from surgery, pre-eclampsia, a pregnancy-related complication marked by high blood pressure and the presence of protein in the urine.

Global Nitric Oxide Supplements Market- By Application

  • Health and Fitness
  • Cosmetics & Personal Care

One of the key reasons driving the market's expansion is the rising demand for L-Arginine as a dietary supplement. Supplemental L-arginine is helpful for a variety of ailments, from inflammation to migraines. L-Arginine is helpful for persons with cardiovascular issues because it relaxes blood arteries. According to research, L-arginine may help to relieve the symptoms of peripheral artery disease, angina, and enhance the health of people who have heart failure. L-Arginine is also known to have an immune-boosting impact, which helps to treat the HIV-related symptoms of weight loss.

Global Nitric Oxide Supplements Market- By Geography & Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • The Middle East and Africa

North America, followed by Europe, commands the majority of the world market for arginine supplements. The pharmaceutical business in these areas is expanding significantly, and rising healthcare costs are likely to drive greater demand for arginine supplements. For instance, in 2015, the total contribution of health care spending to GDP in the United States and Western Europe was approximately 17% and 11.5 percent, respectively.

Additionally, from the years 2016 to 2020, care industries in the U.S. and Western Europe are projected to increase at a CAGR of 4.2 and 4.1 percent, respectively. Additionally, during the course of the projection period supplement markets in North America and Europe are anticipated to post high CAGRs. The pharmaceutical post-highaceutical products are predominantly imported from China into the Western Europe market, which is an import-oriented market.

China and India are the two countries that produce the majority of the arginine supplements sold worldwide. Over the forecast period, India's pharmaceutical production is anticipated to expand by double digits.

As almost 62 percent of the world's population was found in the Asia Pacific (APAC) region. Ageing populations and an increase in the number of kidney and chronic disease patients led to an increase in demand for medications and dietary supplements, which in turn drove the market for arginine supplements.

The demand for arginine supplements is being driven by rising government spending in the healthcare sector, particularly in GCC nations in the Middle East and Africa. Over the forecast period, the market for arginine supplements is anticipated to expand at a consistent CAGR.

Global Nitric Oxide Supplements Market- By Companies

  1. Jarrow Formulas Inc.
  2. Prinova Group LLC.
  3. Glanbia Nutritionals Inc.
  4. NOW Foods
  5. Twinlab Corporation
  6. Infinite Labs
  7. Olympian Labs Inc.
  8. Ajinomoto Group
  9. Scientific Sports Nutrition Ltd.


  • Merger & Acquisition: - In 2020, A 40-year-old manufacturer named Jarrow Formulas has been acquired by private equity company New Mountain Capital.
  • Merger & Acquisition: - In 2019, Watson, a U.S.-based producer and provider of premium bespoke nutrient premix, baking ingredient, edible film, and material conditioning solutions for the nutrition, food and beverage, personal care, and supplement industries, has been bought by Glanbia Nutritionals.

Chapter 1. Global Nitric Oxide Supplements Market – Scope & Methodology

1.1. Market Segmentation

1.2. Assumptions

1.3. Research Methodology

1.4. Primary Sources

1.5. Secondary Sources

Chapter 2. Global Nitric Oxide Supplements Market – Executive Summary

2.1. Market Size & Forecast – (2023 – 2030) ($M/$Bn)

2.2. Key Trends & Insights

2.3. COVID-19 Impact Analysis

       2.3.1. Impact during 2023 - 2030

       2.3.2. Impact on Supply – Demand

Chapter 3. Global Nitric Oxide Supplements Market – Competition Scenario

3.1. Market Share Analysis

3.2. Product Benchmarking

3.3. Competitive Strategy & Development Scenario

3.4. Competitive Pricing Analysis

3.5. Supplier - Distributor Analysis

Chapter 4. Global Nitric Oxide Supplements Market Entry Scenario

4.1. Case Studies – Start-up/Thriving Companies

4.2. Regulatory Scenario - By Region

4.3 Customer Analysis

4.4. Porter's Five Force Model

       4.4.1. Bargaining Power of Suppliers

       4.4.2. Bargaining Powers of Customers

       4.4.3. Threat of New Entrants

       4.4.4. Rivalry among Existing Players

       4.4.5. Threat of Substitutes

Chapter 5. Global Nitric Oxide Supplements Market - Landscape

5.1. Value Chain Analysis – Key Stakeholders Impact Analysis

5.2. Market Drivers

5.3. Market Restraints/Challenges

5.4. Market Opportunities

Chapter 6. Global Nitric Oxide Supplements Market – By Type

6.1. L- Arginine

6.2. L- citrulline

Chapter 7. Global Nitric Oxide Supplements Market – By Application

7.1. Health and Fitness

7.2. Cosmetics & Personal Care

Chapter 8. Global Nitric Oxide Supplements Market- By Region

8.1. North America

8.2. Europe

8.3. Asia-Pacific

8.4. Latin America

8.5. The Middle East

8.6. Africa

Chapter 9. Global Nitric Oxide Supplements Market – Company Profiles – (Overview, Product Portfolio, Financials, Developments)

9.1. Jarrow Formulas Inc.

9.2. Prinova Group LLC.

9.3. Glanbia Nutritionals Inc.

9.4. NOW Foods

9.5. Twinlab Corporation

9.6. Infinite Labs

9.7. Olympian Labs Inc.

9.8. Ajinomoto Group

9.9. Scientific Sports Nutrition Ltd.


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