Biotechnology Market Size (2024 – 2030)

The global biotechnology market was valued at USD 1.5 trillion and is projected to reach a market size of USD 3.53 trillion by the end of 2030. Over the forecast period of 2024–2030, the market is projected to grow at a CAGR of 13%.

Biotechnology is a multidisciplinary discipline that uses the natural sciences and engineering to generate products and services using organisms and their components. Hungarian engineer Károly Ereky coined the phrase in 1919 to refer to the process of turning raw materials into products by employing living organisms. The fundamental idea behind biotechnology is the utilization of biological systems and species, such as bacteria, yeast, and plants, to carry out certain functions or generate useful materials. This field gained prominence in the '90s due to the development of insulin and a better understanding of DNA. Additionally, the human genome project that was completed in 2003 helped in gaining better insights into personalized medicine and genomics. Presently, the market is emerging due to its focus on agriculture and medicine. In the future, with better investments and R&D activities, immense growth is anticipated.

Key Market Insights:

The Indian biotechnology sector was estimated to be worth around 92 billion dollars in 2023. By 2030, the sector was predicted to have a $300 billion market value.

With a turnover of more than six billion euros, Spanish biopharmaceutical producer Grifols ranked among the biggest biotechnology corporations in 2022.

The majority of the projected 436 billion dollars in worldwide biotech medicine sales are produced in the United States and Europe, which are the core biotech sector areas.

With a market valuation of $268.27 billion, Swiss biotech corporation Roche ranked as the world's largest biotech business in November 2022.

Compounds can fail in the final stage by 40%, the intermediate stage by 60%, and the preliminary stage by up to 36%. To tackle this problem, businesses must invest in high-throughput screening technologies for the accurate identification of compounds with desirable properties. Additionally, AI and ML can be used to generate algorithms for predicting efficacy at early stages.

Biotechnology Market Drivers:

Demand for personalized medicine has been facilitating the expansion.

Personalized medicine involves the concept of inventing treatments based on the genetic makeup of an individual. For this, factors like genes, environment, and lifestyle are considered. Customizing medical interventions to the distinct genetic composition of each patient can increase treatment effectiveness, reduce adverse effects, and improve patient care. Because biotechnology has made methods for analyzing and interpreting genetic and molecular data available, it has aided individualized therapy. This enables scientists to find genetic variants and mutations linked to illnesses, which can assist medical practitioners in forecasting treatment reactions, prognosis, and disease susceptibility. High-throughput screening technologies stem cell research, and AI & ML are being used to screen genetic data for the identification of new therapeutic agents. Drugs are developed accordingly.

Advancements in gene editing technologies have been boosting the market.

A set of tools called gene editing, often referred to as genome editing or genome engineering, enables researchers to specifically alter an organism's DNA. These technologies function like scissors to cut and then replace DNA, adding, removing, or changing it at particular places in the genome. Researchers are looking at gene therapies as a possible treatment for cancer, infectious illnesses, and genetic disorders and to create vaccines. In research mouse models, CRISPR has been utilized to fix mutations in genes that cause hereditary tyrosinemia, cataracts, hemophilia, inherited Duchenne muscular dystrophy, cystic fibrosis, and severe combined immunodeficiency. Mutations in the BRCA1 and BRCA2 genes, for example, can cause cancer. However, these mutations can be corrected by genome editing. Besides healthcare, CRISPR has been used for agricultural applications. It is possible to modify crops to generate fewer allergies. Wheat strands without gluten were created using CRISPR, making it suitable for those with celiac disease. Many such industrial applications are being researched to create advanced products for the benefit of humankind.

Biotechnology Market Restraints and Challenges:

Ethical concerns, cost constraints, and bioterrorism are the main issues that the market is currently facing.

The field of biotechnology raises social concerns about technologies like gene manipulation, cloning, and the use of animals for testing. This can create diminished biodiversity for species and crops. In the long run, the consequences are unknown. Additionally, transgenic organisms can be released into the environment, creating serious repercussions. Secondly, high initial investments are vital. This field requires advanced technologies, infrastructure, and other resources. Research and developmental activities have an equal probability of failure. Most of the clinical trials for diseases like cancer and diabetes fail during scrutiny. Thirdly, concerns are raised about the misuse of technologies. Terrorism involving the deliberate release or spread of biological agents is known as bioterrorism. The intentional introduction of viruses, bacteria, or other germs (agents) intended to sicken or kill humans, animals, or plants is known as a bioterrorism assault. This can put the countries at risk.

Biotechnology Market Opportunities:

Biotechnology provides many opportunities in various sectors. One such field is the environment. Environmental biotechnology is a branch of science that develops and applies biological systems and live creatures to solve environmental issues such as pollution, waste management, renewable energy production, and biodiversity preservation. Bio-based fossil fuels, bioplastics, biochemicals, biological enzymes that help in cleaning contaminants, and bioremediation techniques where organisms are introduced to digest certain chemicals and remove toxins are a few such breakthroughs. Secondly, agricultural biotechnology is another emerging field. By using gene editing tools, crops can be altered to have more resistance to pesticides, drought, allergens, and other environmental factors. GMO crops have been gaining prominence. Their nutritional profile is enhanced for better human health. Thirdly, biopharmaceuticals are becoming beneficial. They are sophisticated medications derived from live cells or creatures. They can be produced from biological sources, such as bacteria and filamentous fungi, or extracted from semisynthesized forms. Biopharmaceuticals seldom have adverse effects since they only target particular molecules. When compared to traditional medications, biopharmaceuticals show a high level of activity. For individuals who do not respond well to conventional synthetic medications, biopharmaceuticals can help. Furthermore, bioinformatics tools are being looked upon. Bioinformatics, an interdisciplinary scientific area, creates software tools and methods for interpreting biological data, particularly complicated and large-scale data sets. These tools help in predicting protein structure, developing drugs, understanding the genes that cause a certain illness, and proteomics.

BIOTECHNOLOGY MARKET REPORT COVERAGE:

Biotechnology Market Segmentation: By Technology

• Nanobiotechnology

• Tissue Engineering and Regeneration

• DNA Sequencing

• Cell-based Assays

• Fermentation

• PCR Technology

• Chromatography

• Others

DNA sequencing is the largest growing technology. The technique of figuring out the nucleotide order in DNA is called DNA sequencing. This data is crucial for research in biology. One essential method for classifying and distinguishing terrestrial life forms is DNA sequencing. Understanding human genomic diversity and the genetic components of some disorders is also dependent on it. Secondly, DNA sequences from healthy and mutant samples may be compared to aid in the diagnosis of illnesses like cancer and to direct patient therapy. Sequencing, for instance, can be used to find inherited variations linked to a particular characteristic, vulnerability, or illness. By identifying alterations in certain genomic regions, it can also assist scientists in understanding how particular diseases arise. Additionally, virology, biological systematics, biotechnology, and forensic biology all depend on DNA sequencing. Nanobiotechnology is the fastest-growing segment. The science of nanotechnology is expanding quickly, and it may be used with biotechnology to aid in the diagnosis, treatment, and tracking of illnesses. This combination, known as bionanotechnology, can enhance pharmacological therapy, save costs, and improve medical results. Cancer diagnostics, complex disease therapies, personalized medicine, early-warning tests, and lab-on-a-chip technologies are a few biotechnology uses of nanotechnology. Nucleic acid therapies can also be delivered to immune cells and tumors with the use of nanotechnology.

Biotechnology Market Segmentation: By Application

• Health

• Food & Agriculture

• Natural Resources & Environment

• Industrial Processing

• Bioinformatics

• Others

The largest growing application is the health sector. Biotechnology applications are used for the production of vitamins, toxins, enzymes, hormones (including insulin and interferon), antibiotics, and more. Genetic illness diagnosis is another application. Current medications can be produced more quickly and affordably with the aid of modern biotechnology. Bioinformatics is the fastest-growing category. In the context of clinical trials and pharmaceutical research, bioinformatic analysis has taken on a more crucial role. The confluence of biology and data has created a plethora of prospects for better medication development, better research, and better patient outcomes. Knowing which patients will respond to a given cancer treatment, for example, might help clinicians choose the best course of action for their patients. It can also result in tailored therapy and aid in the identification of pharmacological targets. Additionally, biotechnology, forensic analysis, comparative research, evolutionary studies, and veterinary sciences might benefit from the application of bioinformatics.

Biotechnology Market Segmentation: Regional Analysis

• North America

• Asia-Pacific

• Europe

• South America

• Middle East and Africa

North America is the largest growing market. Countries like the United States and Canada are at the forefront. The primary reason for this is the presence of well-established companies. These players have a global presence that increases revenue. Amgen Inc., Gilead Sciences Inc., Biogen Inc., and Vertex Pharmaceuticals Inc. are the prominent ones. These companies have many patents for various drugs in the field of oncology. Enormous investments are made in research and developmental activities due to economic stability. Besides, advanced tools and resources are accessible. Many prestigious universities are involved in biotech studies to decipher concepts. Asia-Pacific is the fastest-growing market. China, Japan, Australia, and South Korea are at the top. Studies revolving around personalized medicine are rapidly growing in these regions. Many startups are coming up with innovative products and technologies. The rising prevalence of chronic conditions has led to the need for better treatments. Governmental support through schemes, training, and funding has helped in the uplift.

COVID-19 Impact Analysis on the Global Biotechnology Market:

The outbreak of the virus had a positive impact on the market. The main way to prevent the containment of the virus was to develop a vaccine. Many clinical trials were conducted by MNCs and startups to come up with a solution. Most of the funding was allotted to healthcare applications. Many organizations increased their budget for research and developmental activities. Numerous studies were conducted to understand the mechanism of action of the virus. Computational tools in biotechnology, also known as bioinformatics, gained popularity. Collaborations and partnerships were prevalent for accelerating treatment and vaccine development. Diagnostic capabilities saw a surge. Telemedicine became the new norm due to lockdowns, movement restrictions, and social isolation. Digital tools like health tracking and monitoring apps gained tremendous emphasis. Global health initiatives saw a drastic rise. Employment opportunities arose in this sector. During the second half of the pandemic, the bioscience sector in the United States employed 2.1 million people, working in over 127,000 U.S. businesses. Post-pandemic, the market has continued to grow owing to demand and interest.

Latest Trends/ Developments:

The advancement of healthcare delivery and patient care is being expedited by the amalgamation of biotechnology and digital health technologies, including artificial intelligence, big data analytics, and telemedicine. Wearable technology, remote monitoring programs, and digital health platforms streamline healthcare procedures, enhance patient outcomes, and enable tailored therapy.

Key Players:

1. Amgen Inc.

2. Gilead Sciences, Inc.

3. Biogen Inc.

4. Genentech (Roche)

5. Regeneron Pharmaceuticals Inc.

6. Moderna Inc.

7. Vertex Pharmaceuticals, Inc.

8. CSL Limited

9. Novozymes A/S

10. Illumina Inc.

• In March 2024, several focused initiatives were proposed by the Commission to advance biotechnology and biomanufacturing within the EU. In keeping with the communication on the long-term competitiveness of the EU, the document on Building the Future with Nature outlines the obstacles and problems and suggests solutions.

• In November 2023, at the Bengaluru Tech Summit, the Karnataka government unveiled updated biotechnology and animation, visual effects, gaming, comics, and extended reality (AVGC-XR) policies. This policy emphasizes the application of genomics and genome editing and seeks to establish Karnataka as a global center for clinical trials.

• In September 2022, a National Biotechnology and Biomanufacturing Initiative was established by an Executive Order issued by President Biden. This initiative will cut costs for the American people, strengthen supply networks, and generate employment domestically.