Global 3D Bioprinting Market Size (2023 - 2030)

The Global 3D Bio printing Market is estimated to be worth USD 2 Billion in 2022 and is projected to reach a value of USD 5.43 Billion by 2030, growing at a CAGR of 13.3% during the forecast period 2023-2030.

3D bioprinting is an additive manufacturing technique that prints living cells with bio-inks to create structures that replicate the behavior and structure of natural tissues layer by layer. In 3D bioprinting, bio-inks, which can be mixed with living cells, are made of natural or synthetic biomaterials. Scientists are able to investigate the functions of the human body in vitro due to this technology and bioprinted structures. When compared to in vitro studies conducted in two dimensions, 3D bioprinting can be utilized for a wide range of biological applications in the fields of tissue engineering, bioengineering, and materials science. Additionally, this technology is increasingly being utilized for drug development. Bioprinting research is currently focused on clinical settings like 3D-printed skin and bone grafts, implants, and even full 3D-printed organs. Tissue engineering, which aims to produce functional tissue for use in regenerative medicine and drug testing, relies heavily on 3D bioprinting. Tissue regeneration and reconstruction may make it possible to repair or replace damaged tissues and organs.

3D bioprinting technology possesses several advantages. It enables scientists to replicate the real structure of desired tissue or organ. With 3D bioprinting, it is attainable to create patient-specific and organ-specific treatments. The effects of drugs can be examined more accurately with the assistance of this technology. It also helps in reducing animal testing for biomedical research purposes. This technology is capable of automating complex processes, thus resulting in reduced human errors. All-in-all, 3D bioprinting technology has the ability to revolutionize future medical treatment capabilities. As a result of these advantages, the global 3D bioprinting market is estimated to have a fast CAGR during the forecasted period.

Global 3D Bioprinting Market Drivers:

The increasing demand for transplantable tissues and organs is fueling the growth of the global 3D bioprinting market.

The field of 3D bioprinting is growing rapidly in the medical industry. It is the process of using a CAD model to create living tissues and organs. The manner in which medical procedures are carried out could be fundamentally altered by this technology. The ever increasing demand for organ transplants, which is currently transcending the supply of donor organs, could be met by using 3D bioprinting technology, as it may be possible to create transplantable organs ethically and economically. Additionally, 3D bioprinting may be able to cut down on the expense of organ transplants. Therefore, this factor drives the demand for 3D bioprinting technology.

The increasing use of 3D bioprinting technology in the pharmaceutical and cosmetics industry is another factor contributing to the growth of the global 3D bioprinting market.

The pharmaceutical and cosmetics industries are utilizing 3D bioprinting technology more and more. Scientists can now produce 3D structures due to this technology. Complex drug molecules and formulations, as well as cosmetic products like artificial skin, hair follicles, and other tissues, can be easily produced in the pharmaceutical and cosmetics industries with the assistance of this technology. Therefore, this factor also drives the demand for 3D bioprinting technology.

Global 3D Bioprinting Market Challenges:

The global 3D bioprinting market is encountering challenges, primarily in terms of a shortage of skilled professionals and high expenses related to training individuals to operate 3D bioprinting technology. As the need for cutting-edge 3D bioprinting technology grows, the market's expansion has been slowed by a lack of skilled professionals. It is necessary to employ skilled professionals in order to operate and maintain 3D bioprinting technology. Moreover, the companies have to bear a high cost for upskilling individuals regarding the use of 3D bioprinting technology as it is currently a new technology in the market. Thus, these challenges inhibit the growth of the global 3D bioprinting market.

Global 3D Bioprinting Market Opportunities:

The expansion of 3D bioprinting technology to new industries presents a lucrative opportunity in the global 3D bioprinting market. Given the rising demand for 3D bioprinting technology due to the technology's capability of producing complex natural tissue-like 3D structures, major 3D bioprinting companies can stand to gain significantly from this opportunity by expanding their product to new industries, such as the food and beverages industry for the creation of plant-based meat and other meat alternatives, in order to broaden their customer base and boost their overall revenue.

COVID-19 Impact on the Global 3D Bioprinting Market:

The outbreak of the COVID-19 pandemic substantially impacted the global 3D bioprinting market. The implementation of strict lockdowns, traveling restrictions, and social distancing measures across several nations hindered many companies' manufacturing capacities and caused a shortage of skilled workforce. The pandemic caused disruptions in supply chains and distribution of goods and services, which highly affected the sourcing of materials required for 3D bioprinting. Moreover, several research labs were forced to operate at reduced capacity. These factors negatively impacted the growth of the global 3D bioprinting market. However, there has been an increased demand for 3D bioprinting technology for assistance in drug and toxicology testing. Additionally, scientists utilized 3D bioprinting technology to develop 3D bioprinted human micro-tissues infected with the SARS-CoV-2 virus in order to study the virus progression. These factors positively impacted the market's growth. Therefore, the global 3D bioprinting market experienced both challenges and opportunities during the difficult time of the COVID-19 pandemic.

Global 3D Bioprinting Market Recent Developments:

• In April 2023, CollPlant Biotechnologies and Stratasys Ltd. unveiled plans to develop a solution for the bioprinting of tissues and organs. A cooperative development and commercialization agreement has been signed between the two companies to develop a method for bio-fabricating human tissues and organs using CollPlant Biotechnologies' rh-Collagen-based bio-inks and Stratasys Ltd.'s P3 technology-based bioprinter. 
• In December 2022, Essent Biologics, a non-profit biotechnology company, unveiled the availability of its Micronized Bone Matrix (MBM) for applications in tissue engineering and 3D bioprinting. A mineralized allograft bone matrix derived from human ground cortical bone and containing native proteins like collagen type I as well as native elements and minerals like calcium and phosphorus will be provided by Essent Biologics.
• In November 2022, Avay Biosciences Private Limited, an Indian tech start-up that develops 3D bioprinters, launched an indigenous 3D bioprinter to produce human tissues. At the Indian Institute of Science in Bengaluru, the "Mito Plus" bioprinter's initial prototype was installed. Mito Plus is a more advanced version of the start-up's previously developed Bio 3D printer, which was co-founded by an IIT Madras alumnus, based on the prototype from Dr. Bikramjit Basu's research lab at IISc. It is said to be one of India's most advanced 3D bioprinters.

3D BIPRINTING MARKET REPORT COVERAGE:

Global 3D Bioprinting Market Segmentation:

Global 3D Bioprinting Market Segmentation: By Component

• 3D Bioprinters
• Bio-inks

Based on the component, the global 3D bioprinting market is segmented into 3D bioprinters and bio-inks. In 2022, the 3D bioprinters segment held the highest market share. The growth can be attributed to the 3D bioprinters being the primary component used for the 3D bioprinting of tissues and organs. The use of 3D bioprinters enables scientists to fabricate well-defined 3D scaffolds seeded with cells in a faster, more economical, and high-throughput manner. The rising demand for 3D bioprinters in the applications of tissue engineering, regenerative medicine, drug printing, clinical transplantation, toxicology screening, and high-throughput assays propels this segment's growth. 

Global 3D Bioprinting Market Segmentation: By Technology

• Magnetic Levitation
• Inkjet-based
• Syringe-based
• Laser-based
• Others

Based on the technology, the global 3D bioprinting market is segmented into magnetic levitation, inkjet-based, syringe-based, laser-based, and others. In 2022, the inkjet-based segment held the highest market share. The growth can be attributed to the advantages of inkjet-based technology over other technologies, including higher speed, lower cost, higher resolution, and wider availability. Inkjet bioprinting, also called drop-on-demand printing, is a non-contact printing method that makes use of thermal, piezoelectric, or electromagnetic forces to disperse droplets of diluted solutions. The conventional inkjet process utilized by desktop inkjet printers, in which individual droplets are utilized to pattern a substrate, serves as the foundation for inkjet bioprinting technology.

Global 3D Bioprinting Market Segmentation: By Region

• North America
• Europe
• Asia-Pacific
• Rest of the World

North America held the largest share of the global market for 3D bioprinting in 2022. The well-established healthcare infrastructure in North American nations like the United States and Canada, the increasing investments made by government and private organizations in 3D bioprinting technology research and development activities, and the region's high adoption rate of advanced technologies all contribute to the region's growth. Additionally, significant market players such as 3D Systems, Aspect Biosystems, Nano3D Biosciences, Inc., EnvisionTEC, and Allevi, Inc. are located in the region.

Asia-Pacific is anticipated to be the fastest-growing region during the forecast period, owing to the increasing demand for personalized medicine, growing investments in 3D bioprinting technology research and development, and a growing focus on the applications of 3D bioprinting in tissue engineering and regenerative medicine.

Global 3D Bioprinting Market Key Players:

1. Bico Group AB (Sweden)
2. CollPlant Biotechnologies Ltd (Israel)
3. 3D Systems (United States)
4. Aspect Biosystems (Canada)
5. GeSIM GmbH (Germany)
6. Nano3D Biosciences, Inc. (United States)
7. Stratasys, Ltd. (Israel)
8. EnvisionTEC (United States)
9. Allevi, Inc. (United States)
10. Voxeljet AG (Germany)