Sanger Sequencing Diagnostic Services Market Size (2024-2030)

The Sanger Sequencing Diagnostic Services Market was valued at USD 1.92 billion in 2023 and is projected to reach a market size of USD 6.3 billion by the end of 2030. Over the forecast period of 2024-2030, the market is estimated to grow at a CAGR of 18.5%. 

In recent past years, Sanger sequencing is renowned for its accuracy and reliability in diagnosing high-quality DNA sequencing data. However, Sanger sequencing is typically restricted in terms of the number of samples that can be prepared simultaneously. Additionally, Sanger sequencing, with its ability to accurately sequence specific genes or regions of interest, plays a pivotal role in diagnostic testing, identifying disease-causing mutations and monitoring treatment response. The growing adoption of clinical genomics provides opportunities for the Sanger sequencing market. Although, obtaining regulatory approvals and reimbursement coverage for Sanger sequencing-based tests can be challenging, needing time and resources to navigate the regulatory environment which acts as a bottle neck for the growth of the market. “Diagnostics” dominates the application segment of the Sanger Sequencing market owing to the rising demand for better methods of diagnosis and testing in patients.

Key Market Insights:

• China is projected to witness major growth in the near future, due to increase in R&D investment and surge in applications of Sanger’s sequencing. Additionally, the Chinese region offers noteworthy opportunities for the venture capitalists and investors, as the developed markets are comparatively saturated.
• The introduction of large-scale research utilizing NGS methods results in the creation of new core information concerning cancer precision medicine. The healthcare business strives to enhance technology in order to reduce health issues and extend human longevity. Resultantly, worldwide companies, as well as hundreds of biotechnology start-ups throughout the world, are trying to help mankind by inventing innovative healthcare solutions.
• Many of the emerging biotechnology and genetics start-ups are employing DNA sequencing technologies for a range of purposes. These new growing firms offer sequencing services for human and animal genomes. Personal Genomic Diagnostics Inc., based in Baltimore, Maryland, expertise in genome analysis of human cancers. Using sequencing methods and technology, the business makes a patient-specific cancer analysis.

Sanger Sequencing Diagnostic Services Market Drivers:

• Technological developments in the industry is pushing the market forward.

The market for Sanger's sequencing services is expanding due to technological developments in sequencing methods and its diagnostic services, benefits of Sanger's sequencing, and an increase in genome mapping initiatives. In addition, sequencing applications and deployment in R&D expenditure have added to the market's expansion.

• Active Research and development (R&D) activities are fueling growth in the market.

The increased focus that vendors are paying towards developing countries like China, India, and Southeast Asia is anticipated to promote market expansion. The market is expected to observe significant growth in the near future as a result of rising R&D expensing and a boom in Sanger sequencing applications.

• Rise in genetic illness is greatly impacting and increasing the need for these services globally.

The wide utilisation of genetic testing on vertebrates and plants, other factors influencing the market's growth include the rising prevalence and familiarity of genetic illnesses and tailored medicine.

Sanger Sequencing Diagnostic Services Market Restraints and Challenges:

NGS technologies have revolutionized genetic sequencing by detecting high-throughput sequencing of entire genomes or exomes at a lower cost per base. Resultantly, the Sanger sequencing market faces competition from NGS platforms, which offer wider applications and higher throughput capabilities. New sequencing technologies are becoming obtainable, such as single-molecule sequencing, which offer faster and more affordable services than traditional Sanger sequencing Diagnostic Services. This has resulted in increased competition and has put downward pressure on the Sanger Sequencing Diagnostic Service market.

Sanger sequencing is congenial for targeted sequencing of specific genes or regions of interest. However, it may not be as suitable for whole-genome or exome sequencing due to its restricted throughput and higher cost per base. This can restrict its utilisation in certain research or clinical settings.

Sanger Sequencing Diagnostic Services Market Opportunities:

The field of Genomics is continuously evolving, with ongoing research and development efforts in areas like cancer genomics, rare genetic disorders, and infectious diseases. Sanger sequencing is a valuable and significant tool for researchers to validate and confirm genetic variants discovered through next-generation sequencing technologies. The demand for Sanger sequencing in research and development activities presents opportunities for market development.

The Global Sanger Sequencing Service Market is directed by the increasing demand for high-throughput sequencing solutions in the Life Science and Healthcare industries. These solutions are being applied in research activities, drug development, and clinical diagnosis. With advancements in genomic research and personalized medicine, there is a growing necessity for accurate and reliable genetic sequencing technologies like Sanger sequencing and Diagnostic Services. This market opportunity arises from the growing demand for genomic testing to guide customized treatment plans for various diseases. The growing demand for personalized medicine, along with the rising need for accurate and rapid diagnosis of genetic diseases are expected to add to the growth of the market. The growing need for faster DNA sequencing methodologies, the development of new technologies such as next-generation sequencing (NGS) and the increasing deployment in Research & Development activities are some of the other factors driving the Global Sanger Sequencing Diagnostics Service Market.

SANGER SEQUENCING DIAGNOSTIC SERVICES MARKET REPORT COVERAGE:

Sanger Sequencing Diagnostic Services Market Segmentation:

Sanger Sequencing Diagnostic Services Market Segmentation By Type:

• Instruments
• Reagents
• Software & Services

Instruments are the hardware components used in Sanger sequencing for performing chemical reactions and physically creating the DNA strands. They aid in automated sequencing processes, such as capillary electrophoresis, thermocyclers, and sequencing workstations. These instruments are designed to be user friendly and can be applied even with minimal training.

Reagents are chemicals utilised in the Sanger sequencing process. These reagents act as catalysts that enable DNA synthesis, replication, and analysis. Some major reagents used in Sanger sequencing services include Taq polymerase, trace buffers, enzymes, fluorescent markers, and primers.

Software and services are used to assist with the analysis and interpretation of large data sets created from Sanger sequencing experiments. Scenarios of software used for Sanger sequencing services include Bio-Rad software packages, Illumina software packages, and Qiagen software. Services used for this purpose involve data management, quality assessment, and interpretation.

Sanger Sequencing Diagnostic Services Market Segmentation By End User:

• Academic and Research Institutes
• Hospitals and Clinics
• Pharmaceutical and Biotechnology Companies

Academic & Research Institutes are major customers of Sanger Sequencing services, as they need comprehensive and detailed analysis for their research and studies. These services come in several forms, including gene sequencing, DNA sequencing, and other genomics services. Furthermore, due to the large number of academic and research projects, these institutes require more accurate, budget-friendly and high-throughput sequencing technology and services.

Hospitals & Clinics need efficient and reliable technology for genetic testing, diagnosis and counselling for the purpose of early detection and preventive care. Sanger Sequencing Service helps them to accurately diagnose the genetic cause of a disorder or diagnosis using a cost-effective method and thereby strategically manage clinical resources and improve patient care.

Pharmaceutical & Biotechnology Companies apply Sanger Sequencing services to create personalized treatments and therapies to cure complex diseases. These services enable them to better understand the drug interaction with the genome, as well as analyse drug efficacy upon different patients to aid them focus their resources on successful therapeutic products.

Sanger Sequencing Diagnostic Services Market Segmentation By Technology

• Sanger Sequencing
• Next-Generation Sequencing

Sanger sequencing is a traditional form of DNA sequencing that enables researchers to diagnose the order of nucleotides or bases in a single-stranded DNA molecule. It does this by making a series of fragment lengths, then uses chain-termination techniques and a DNA-dependent DNA polymerase to add labelled nucleotides to the end of these fragments. The chain stops when a labelled or unlabelled nucleotide is incorporated, and the fragments are then differentiated into individual pieces according to size, after which they are identified according to their respective labels.

Next-Generation Sequencing (NGS) is a powerful and latest technology used in the sequencing of millions of DNA strands simultaneously. It is a more advanced form of DNA sequencing that is more budget-friendly, faster, and more accurate than traditional methods. This technology is utilised to identify disease-causing genes, sequence several genomes in parallel and determine the function of multiple genes at once. NGS works by using massively parallel sequencing of DNA fragments, which is accomplished through high-throughput DNA sequencing, software, and robotics that analyse and decode the generated data.

Sanger Sequencing Diagnostic Services Market Segmentation By Region:

• North America
• Asia-Pacific
• Europe
• South America
• Middle East and Africa

North America is predicted to dominate the Sanger sequencing market owing to the rising number of geriatric population and advancing medical technology adoption. This is driven by the increasing need for personalized medicine, as well as the excess use of genomic sequencing in research and clinical applications. Furthermore, the availability of advanced sequencing technologies and the growing number of partnerships between academic and industry partners are also contributing to the development of the market.

Asia-Pacific is expected to experience significant growth during the forecast period of 2023 to 2030 due to an expansion in research and development expenditure and an increase in the utilization of Sanger sequencing. Also, the region's large population and the obtainability of advanced sequencing technologies are also contributing to the growth of the market. The market is further driven by the rising number of collaborations between public and private organizations.

COVID-19 Impact Analysis on the Sanger Sequencing Diagnostic Services Market:

Outbreak of COVID-19 posed crucial challenges in all the sectors including Sanger Sequencing Diagnostic sector across the globe. It has resulted in the negative growth of the Sanger Sequencing services as supply chain disruptions due to trade regulations and restrictions affected the product demand. 

Latest Trends:

Personalized medicine is an emerging trend in the Healthcare industry which eyes on providing customized treatments to individuals based on their personal genetic make-up. As the technology for Sanger sequencing is becoming more modernized, there is an increasing demand for personalized medicine, as Sanger sequencing enables more detailed data for the development of treatments for different types of diseases.

Sanger sequencing is increasingly being used in drug discovery and development, as it provides a comprehensive and extensive look at the genetic sequence of a particular organism. This permits researchers to gain greater insight into the genetic make-up of a particular organism, which can lead to the birth of new drugs and treatments. Sanger sequencing is also being used to figure out new gene targets, which can lead to the development of more targeted treatments.

Key Players:

1. Thermo Fisher Scientific Inc (U.S.)
2. Source BioScience (U.K.)
3. GenScript (U.S.)
4. LGC Limited (U.K.)
5. CeMIA (U.S.),
6. Quintara Biosciences (U.S.)
7. GenHunter Corporation (U.S.)
8. GENEWIZ (U.S.), Nucleics (U.K.)
9. SciGenom Labs Pvt. Ltd (India)