The Antibody-Drug Conjugates (ADCs) in oncology market refers to a class of targeted cancer therapies that combine monoclonal antibodies with potent cytotoxic agents. These agents are designed to selectively deliver the cytotoxic drug to cancer cells, minimizing damage to healthy cells. ADCs offer high specificity and improved therapeutic outcomes, representing a paradigm shift in cancer treatment.
Disruptive Impact and Opportunities:
ADCs are transforming oncology treatment paradigms by offering precision therapies that are both targeted and effective. Their ability to deliver cytotoxic agents directly to tumor cells without affecting surrounding healthy tissues presents significant opportunities in terms of improving patient outcomes and reducing adverse side effects. ADCs also provide new treatment options in cancers that were previously hard to treat. The market potential is considerable, with a focus on new, safe, easy-to-administer therapies that promise substantial efficacy. ADCs are poised to address unmet needs across a range of cancers, from breast and lung cancers to lymphomas and hematological malignancies.
Teliso-V
Telisotuzumab vedotin
NBE-002
Ladiratuzumab Vedotin
Disitamab vedotin (RC48) + PD1
SHR-A1811 + pyrotinib maleate
ARX788 + pyrotinib maleate
Zynlonta
Key Companies:
Seagen
AstraZeneca
Daiichi Sankyo
Merck
RemeGen
Jiangsu-Hengrui Medicine
Zhejiang Medicine/NovoCodex
NBE-Therapeutics
ImmunoGen Inc.
· Monoclonal Antibodies (mAbs)
HER2-targeted ADCs
CD30-targeted ADCs
CD33-targeted ADCs
Other mAb-targeted ADCs
· Linker Technology
Cleavable Linkers
Non-Cleavable Linkers
· Payloads (Cytotoxic Drugs)
Maytansinoid-based Payloads
Auristatin-based Payloads
Calicheamicin-based Payloads
Duocarmycin-based Payloads
Other Cytotoxic Agents
· Intravenous (IV) Administration
Standard Infusion
Extended Infusion
· Subcutaneous (SC) Administration
· Oral Administration
What’s in It for You?
Gain insights into emerging ADC therapies poised to disrupt oncology treatment landscapes.
Understand competitive dynamics with a detailed overview of key players and their strategies.
Identify market opportunities based on emerging drugs and evolving treatment paradigms.
Anticipate market trends and plan for future investment and R&D directions.
Access a comprehensive analysis of drug candidates currently in development and their market potential.
Antibody–drug Conjugates (ADCs) in Oncology Market - Executive Summary
Introduction
Objectives
Key Findings
Market Size 2025 & 2030: By Key Country (10MM)
Global Market Size 2025 & 2030: By Key Segment
Key Investments & Startup Analysis
Research Methodology
Understanding the Disease
Disease Overview
Classification
Signs and Symptoms
Risk Factors
Causes
Disease Biology & Digital Innovations
Stages & Staging System
Diagnostic Algorithm
Current Treatment Practices & Algorithm
Current Standard of Care and Treatment Gaps
Patient Demographics and Treatment Pathways
Guidelines
Unmet Needs
Epidemiology and Patient Population
Epidemiology Key Findings
Assumptions and Rationale: 10MM
Epidemiology Scenario: 10MM
U.S. Epidemiology Scenario
EU-5 Epidemiology
U.K. Epidemiology Scenario
Germany Epidemiology Scenario
France Epidemiology Scenario
Italy Epidemiology Scenario
Spain Epidemiology Scenario
Japan Epidemiology Scenario
China Epidemiology Scenario
Australia Epidemiology Scenario
India Epidemiology Scenario
Real-world Data & Real-world Evidence
Drug Development Landscape
Existing Key Drug Candidate Profiles/ Marketed Therapies
Competitive Analysis and Differentiation
Overview of Similar/Competing Drugs in Clinical Trials
Future Trends and Emerging Drugs
Regulatory Strategy and Potential Challenges
Regulatory Pathways in Key Markets
Anticipated Regulatory Hurdles and Mitigation Strategies
Case Studies in Oncology Drug Regulation
Impact of Potential Changes to Regulatory Framework
Commercial Landscape
Market Size & Growth Rates
Key Approvals & Anticipated Loss of Exclusivity
PESTLE & Porter’s Five Forces Analysis
Market Shares, Positioning/Ranking
Market Drivers
Identification of Threats
Digital Evolution in Commercialization
Market Segmentation
Pricing, Reimbursement, and Access
Competitive Pricing Analysis
Reimbursement Landscape and Challenges
Strategies for Market Access and Equity
Patient Spending/Expenditure Analysis
Future Trends, Disruptions, and Opportunities
Analysis of Emerging Trends
Technological Impact
Impact of Potential Market Disruptors
Opportunities for Future Development and Expansion
Considerations for Investment Opportunities
Global Market Dynamics
Regional Regulatory Disparities
Cross-Border Partnership Strategies
Global Supply Chain Dynamics
Case Studies: Success and Failure in Global Markets
Strategies for Global Expansion and Localization
Company Profiles
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