Ampicillin Sodium and Cloxacillin Sodium Market Size (2023-2030)

Global Ampicillin Sodium and Cloxacillin Sodium Market is estimated to be worth USD 35.2 Billion in 2022 and is projected to reach a value of USD 54.8 Billion by 2030, growing at a steady CAGR of 5.7% during the forecast period 2023-2030.

Ampicillin and cloxacillin are types of antibiotics belonging to the class of medications called penicillins that are used in the treatment of numerous bacterial infections. Ampicillin was developed to address the issue of antimicrobial resistance and to expand the range of penicillin-type antibiotics in effectively treating bacterial infections. Ampicillin can also be administered orally as it is able to resist the effects of stomach acid in contrast to some antibiotics. On the other hand, cloxacillin sodium is the sodium salt form of cloxacillin, a semi-synthetic antibiotic that is a chlorinated derivative of oxacillin. Cloxacillin is usually taken orally in the form of capsules or tablets, just like regular medication. However, in a hospital setting, it can also be administered as an injection.

The combination of ampicillin and cloxacillin, called AMPICILLIN+CLOXACILLIN, is used in the treatment of bacterial infections in various parts of the body, including the ears, nose, throat, bones, respiratory tract, pelvis, urinary tract, skin, and soft tissues, as well as infections in wounds after surgery. The combination is referred to as a broad-spectrum antibiotic owing to its effectiveness against both gram-positive and gram-negative bacteria, including S pneumoniae, L monocytogenes, M catarrhalis, N gonorrhea, N meningitidis, and others. It helps in preventing the formation of a protective layer that bacteria require to survive. When the formation of the protective layer is stopped, the bacteria cannot survive and are killed off, thereby, helping in treating and preventing bacterial infections.

Global Ampicillin Sodium and Cloxacillin Sodium Market Drivers:

The growing use of AMPICILLIN+CLOXACILLIN in treating several bacterial infections is fueling the growth of the global ampicillin sodium and cloxacillin sodium market.

AMPICILLIN+CLOXACILLIN medication is used to treat various infections, including respiratory infections, such as pneumonia, severe inflammation of the bronchial tube lining, and childbirth-related infections like fever caused by a uterine infection during delivery. It can also be used to treat other infections, including blood and bone infections, as well as ear, nose, and throat infections. This medication contains two active ingredients, ampicillin, and cloxacillin, both of which work by damaging the bacterial cell wall. Additionally, AMPICILLIN+CLOXACILLIN can be used to prevent and treat bacterial infections in premature or newborn babies and to treat wound and respiratory system infections after surgery. Therefore, this factor drives the demand for ampicillin sodium and cloxacillin sodium.

The increasing healthcare expenditure is another factor contributing to the growth of the global ampicillin sodium and cloxacillin sodium market.

Both governmental and non-governmental organizations are investing heavily in research and development to address the growing number of individuals afflicted with bacterial infections. The objective is to develop new regulations such as that the approval process can be expedited and funding can be obtained more easily. This regulatory evolution is intended to create novel antibiotics for more efficient treatment of these illnesses. Therefore, this factor also drives the demand for ampicillin sodium and cloxacillin sodium.

Global Ampicillin Sodium and Cloxacillin Sodium Market Challenges:

The global ampicillin sodium and cloxacillin sodium market is encountering challenges, primarily in terms of antibiotic resistance. Antibiotic resistance poses a considerable threat to global health, food security, and development. It can impact anyone, regardless of their age or location, as it occurs naturally but is expedited by the misuse of antibiotics in humans and animals. This can lead to longer hospital stays, greater medical expenses, and higher mortality rates. Thus, these challenges inhibit the growth of the global ampicillin sodium and cloxacillin sodium market.

COVID-19 Impact on the Global Ampicillin Sodium and Cloxacillin Sodium Market:

The outbreak of the COVID-19 pandemic substantially impacted the global ampicillin sodium and cloxacillin sodium market. The pandemic caused disruptions in supply chains and distribution of goods and services, which highly affected the production and distribution of AMPICILLIN+CLOXACILLIN antibiotics. This factor negatively impacted the growth of the global ampicillin sodium and cloxacillin sodium market. However, the pandemic accelerated the use of AMPICILLIN+CLOXACILLIN antibiotics in the management of asymptomatic, mild, moderate, and severe COVID-19 disease with or without complications. These factors positively impacted the market's growth. Therefore, the global ampicillin sodium and cloxacillin sodium market experienced both challenges and opportunities during the difficult time of the COVID-19 pandemic.

Global Ampicillin Sodium and Cloxacillin Sodium Market Recent Developments:

• In March 2023, Glenmark Pharmaceuticals, an India-based multinational pharmaceuticals company, unveiled that the US Food & Drug Administration (USFDA) has approved the distribution of a generic version of Pfizer's Cleocin capsules, which is an antibiotic drug.
• In September 2022, GSK plc, a UK-based multinational pharmaceutical and biotechnology company, signed an exclusive license agreement with Spero Therapeutics, a US-based a multi-asset, clinical-stage biopharmaceutical company, for the latter’s tebipenem pivoxil hydrobromide (tebipenem HBr), a late-stage antibiotic used to treat severe urinary tract infections.
• In March 2021, Cipla Therapeutics, a specialty institutional division of Cipla USA, entered into an agreement with SIGA Technologies, Inc., a US-based pharmaceutical company, to develop novel antibiotics, particularly ones that target drug-resistant microbes.

AMPICILLIN SODIUM AND CLOXACILLIN SODIUM MARKET REPORT COVERAGE:

Global Ampicillin Sodium and Cloxacillin Sodium Market Segmentation:

Global Ampicillin Sodium and Cloxacillin Sodium Market Segmentation: By Route of Administration

• Oral
• Intramuscular 
• Intravenous

In 2022, the oral segment held the highest market share. The growth can be attributed to the convenience and cost-effectiveness of the oral route of administration of AMPICILLIN+CLOXACILLIN antibiotics. These antibiotics are administered orally in the form of capsules, tablets, syrup, or oral drops, particularly in cases of infections that are susceptible to the medication. These forms of antibiotics help in destroying or slowing down the growth of bacteria before it becomes severe.

Global Ampicillin Sodium and Cloxacillin Sodium Market Segmentation: By Application

• Endocarditis 
• Meningitis 
• Pneumonia
• Septicemia
• Osteomyelitis 
• Others

In 2022, the pneumonia segment held the highest market share. The growth can be attributed to pneumonia being a common respiratory infection caused by bacteria, viruses, or fungi. Pneumonia infection causes inflammation in the air sacs located in one or both lungs. This inflammation can cause a buildup of fluid or pus in the air sacs, which leads to symptoms such as coughing with phlegm or pus, fever, chills, and difficulty breathing. It can cause mild to life-threatening illness in individuals of all ages. Pneumonia can be treated with AMPICILLIN+CLOXACILLIN medications, with the route of administration depending on the severity of the infection.

Global Ampicillin Sodium and Cloxacillin Sodium Market Segmentation: By Distribution Channel

• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies

In 2022, the hospital pharmacies segment held the highest market share. The growth can be attributed to hospital pharmacies being a significant distribution channel for AMPICILLIN+CLOXACILLIN antibiotics as they are often prescribed for patients admitted to hospitals. The hospital pharmacy is responsible for procuring and dispensing these antibiotics. This makes hospital pharmacies a crucial segment of the global ampicillin sodium and cloxacillin sodium market.

Global Ampicillin Sodium and Cloxacillin Sodium Market Segmentation: By Region

• North America
• Europe
• Asia-Pacific
• South America
• Middle East & Africa

The region of North America dominated the global ampicillin sodium and cloxacillin sodium market in the year 2022. The rising incidence of bacterial infections, such as pneumonia, gonorrhea, endocarditis, syphilis, salmonellosis, and others, the presence of well-established healthcare infrastructure in nations, such as the United States and Canada, and the increasing investments by the governments in research and development activities are some of the factors propelling the region's growth. Additionally, North America is home to several significant market players, including Abbott Laboratories, AdvaCare Pharma, Teva Pharmaceuticals USA, Inc., Pfizer Inc., and Mylan Pharmaceuticals Inc.

Due to the increasing prevalence of bacterial infections, the rising healthcare expenditure, and the strong presence of major market players, including Cipla Limited, Cadila Pharmaceuticals, and Alkem Laboratories, the region of Asia-Pacific is anticipated to expand at the fastest rate over the forecast period.

Global Ampicillin Sodium and Cloxacillin Sodium Market Key Players:

1. Cipla Limited (India)
2. GlaxoSmithKline plc (United Kingdom)
3. Cadila Pharmaceuticals (India)
4. Abbott Laboratories (United States)
5. AdvaCare Pharma (United States)
6. Alkem Laboratories (India)
7. Glenmark Pharmaceuticals Limited (India)
8. Intas Pharmaceuticals Limited (India)
9. Torrent Pharmaceuticals Ltd (India)
10. Wellona Pharma (India)